Diagnostic power of aortic elastic properties in young patients with Marfan syndrome

Diagnostic power of aortic elastic properties in young patients with Marfan syndrome

BACKGROUND: In patients with Marfan syndrome, progressive aortic dilation implicates a still-unpredictable risk of life-threatening aortic dissection and rupture. We sought to quantify aortic wall dysfunction noninvasively, determine the diagnostic power of various aortic parameters, and establish a diagnostic model for the early detection of aortic abnormalities associated with Marfan syndrome.

METHODS: In 19 patients with Marfan syndrome (age, 17.7 ± 9.5 years) and 19 age- and sex-matched healthy control subjects, computerized ascending and abdominal aortic wall contour analysis with continuous determination of aortic diameters was performed out of transthoracic M-mode echocardiographic tracings. After simultaneous oscillometric blood pressure measurement, aortic elastic properties were determined automatically.

RESULTS: The following ascending aortic elastic parameters showed statistically significant differences between the Marfan group and the control group: (1) decreased aortic distensibility (P

Politicians go where angels fear to tread

The Schiavo fiasco is still hanging around in the news, but it seems that the tables may be turning on GWB and Congress who were so quick to step into a place they never should have been.

I’m not the only one that thinks that our political system is careening wildly out of control. We need less governmental interference, not more.

USATODAY.com – Politicians might feel repercussions of Schiavo case

Public opinion polls say a majority of the country supported the right of Schiavo’s husband, Michael, to remove her feeding tube. “There could be a real backlash against this intervention in the Schiavo case. The public is not at all happy about this,” said Andrew Kohut, director of the Pew Research Center for the People and the Press.

Bush’s approval rating took a 7-point dip in USA TODAY/CNN/Gallup Polls taken before and after he signed the Schiavo bill.

The intervention by Congress in the Schiavo matter has roiled conservatives. Religious conservatives largely supported the action, while economic conservatives seem to resent federal involvement in what they see as a private tragedy.

In a CBS News poll, 82% of Americans said Congress and President Bush should have stayed out of the matter; 74% said Congress was playing politics with the issue.

The USA TODAY/CNN/Gallup Poll found the biggest drops in Bush’s approval rating came among self-described conservatives, churchgoers and men under 50.